At today's first session of the British Cardiovascular Society in London, Cambridge Theranostics announced its release of a new pill, Ateronon™, which has reduced has reduced the oxidation of LDL cholesterol by as much as 90 percent in two months in clinical trials. Ateronon is being marketed as a food supplement, as it is a natural product made from tomato skins -- tangerine tomato skins to be exact.
It has long been known that Lycopene, found in high concentration in tomato skins, is good for your heart, but it has been difficult to find a way for the body to absorb it successfully enough to use it as a food supplement. Cambridge Theranostics, a spin-off of Cambridge University, overcame that barrier by using a special kind of tomato skins, those of the tangerine tomato, grown most abundantly in Italy. Test results have shown that the pill reduces the oxidation of LDL, or bad cholesterol, which leads to the collection of plaque along artery walls, known as atherosclerosis.
Tangerine Tomato. (Credit: W. Atlee Burpee & Co.)
Atherosclerosis is the major cause of strokes and heart attacks. It causes arteries to narrow, restricting blood supply to the heart , brain, and legs. Ateronon is the first formula proven to halt the oxidation of LDL cholesterol, recognized as the key process of atherosclerotic build-up, which can occur even in patients without raised cholesterol levels.
Ateronon is a 7mg pill to be taken daily for £1 each, about $1.6, and is now available online at Ateronon.com.
Ateronon.com via DailyMail Online
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Even though you say "Reduces
Submitted on June 1st, 2009 by AnonymousEven though you say "Reduces bad cholesterol by 90%" ... the website only ever says: "reduces the oxidation of LDL cholesterol".
Are those two things the same?
Reducing LDL cholesterol
Submitted on June 1st, 2009 by Boomer BabeYes, LDL cholesterol is called "bad" cholesterol because it can form plaque along the walls of the arteries, leading to atherosclerosis.
No, those things are not the
Submitted on June 2nd, 2009 by AnonymousNo, those things are not the same. With this supplement, your LDL cholesterol levels will still be high, but it's just that the oxidation (which is what causes it to block to your arteries) of LDL cholesterol is reduced by a whopping 90%.
It does mean that we need a better and easier way to measure LDL oxidation. Some people have very low LDL levels, yet their bodies oxidise the LDL that's there more aggresively than others.
Wim
Its well known that tomatoes are good for you
Submitted on June 2nd, 2009 by AnonymousThis looks like a clever gimmick to me. Its been well known for a number of years that eatling lots of tomatoes can be "good for you" for a number of reasons, not the least is that they contribute to your "Five a Day", contain no fats especially saturated fats etc. It may be true that the active "ingredient" is more difficult to absorb than this product but eating lots of fresh tomatoes is much more fun and interesting. I really enjoy ripe tomatoes and am willing to pay a little more for the "on the vine" type.
masterchef
(yes that`s right my nickname describes what I am)
http://photosoffood.co.uk/wordpress
Well, if you're willing and
Submitted on June 2nd, 2009 by AnonymousWell, if you're willing and able to eat 3 kilos of tomatoes a day (that's the equivalent of one pill) and can buy these for a quid a day, you'd be right.
ModestMouse
(Yes, that's right,my nickname describes what I am)
Thanks Wim... that's what I
Submitted on June 2nd, 2009 by AnonymousThanks Wim... that's what I was curious about.
So the benefit of these pills will not be reflected in our standard LDL cholesterol testing. The number will not change.
Ateronon has not and does
Submitted on June 2nd, 2009 by AnonymousAteronon has not and does not claim to reduce LDL cholesterol by over 90% - Aterronon has made this clear however the media has so far been a bit confused about this.
Ateronon inhibits the oxidation of LDL cholesterol by over 90%, after 2 months of daily use.
So what's the difference?
Cholesterol is something we all have and it isn't necessarily bad. It becomes dangerous when it is 'oxidised' by free radicals in the blood. This damage means that it is more likely to stick to the inside of the arteries and narrow the arteries.
People get tested for cholesterol because they 'high cholesterol' presents a greater risk. But does not mean narrowed arteries. Someone can have low cholesterol, but if they have aggressive oxidation happening, they can have plaque build up and narrow arteries.
So, Ateronon works by inhibited the oxidation process, thereby stopping the major cause that plaque builds and narrows arteries.
So then what is the bottom line
Submitted on June 3rd, 2009 by AnonymousDoes this mean that the LDL stays in the blood, but nothing else happens?
bottom line
Submitted on June 3rd, 2009 by Boomer BabeLDL levels may be affected positively, as they generally are lowered when
antioxidants are added to the diet, but that is not what the Ateronon study is claiming. Changing dietary habits is only effective at reducing LDL for some persons. That is why people take statin drugs.
The bottom line is that Ateronon is a very powerful ANTI-oxidant which is, according to the product research, effective at keeping the LDL from getting sticky and hard, forming arterial plaque.
Here are a few one-page resources you might want to check out as knowledgeable sources of information about cholesterol:
National Heart Lung & Blood Institute
American Heart Association
High cholesterol can be good ?
Submitted on June 9th, 2009 by AnonymousI am confused. .. I have read [see this link] http://www.westonaprice.org/moderndiseases/benefits_cholest.html
...that high cholesterol is not a bad thing. Mine is / was 8.4, now down to 2.8 with atorastatin.
Taking of lowering drugs are not needed, just a healthy diet and plenty of exersise is all that is needed. ???
But now this paper has been released
Does anyone know the real truth?
try this
Submitted on June 9th, 2009 by AnonymousFirst some things to know about lycopene:
1. Its water insoluble: But it will dissolve in organic solvents and Oil.
2. There is a fair amount of lycopene in tomato paste: (4.6-9.1mg/ TBSP) or (.29 - .57 mg / g paste) *
3. In tomato products it is about 4x more bio-available when cooked.
Some things to know about Ateronon:
1. Ateronon will cost about 2$/ pill or about 60$/ mo. **
2. Ateronon has only 4-6mg of lycopene. But showing amazing results compared to other tomato products.
So the goal is to increase the Bio-Availability of lycopene without paying much money. So we would want to do the following:
1. Cook the tomato or use precooked tomato paste.
2. Emulsify the lycopene with either emulsifiers or surfactants.
I can't find any patent information on Ateronon so this analysis is going to be based off of their product ingredient page:
There were 3 noteworthy ingredients (after lycopene):
1. Polysorbate is listed as an ingredient : So we know which emulsifier they are using....
2. Soy - Protein an Emulsifier
3. Whey Protein (from milk) - Another protein emulsifier
From here it isn't really rocket science to put together a wonderful tomato paste... Our ingredient list will look as follows:
1. Tomato Paste without added Salt (about $.5/ 100grams)
2. An oil : Olive Oil
3. Some emulsifier (Some combination of : Tween, PEG3350(miralax), some soy)
Then we probably want to:
1. Warm sauce and Oil; mixing together very very well.
2. Add emulsifier to create the oil / water emulsion; then mix lots more.
I guess that the trick would be to make a couple of weeks worth at one time then store it in a jar in a fridge. I'm not really sure what a good ratio of all of the ingredients would be.... Maybe 6 parts tomato paste, 2 parts oil and 1 part emulsifier. Or maybe it would be radically different...
Its as easy as that. And yes, it looks like Ateronon's study claimed 90% LDL oxidation reduction.
* There was some discrepancy about how much lycopene is in your run of the mill tomato paste. The higher number is from http://1stholistic.com/nutrition/vkb/lycopene.htm and the lower number is from: http://www.nutritiondata.com/facts/vegetab...products/2689/2 I think that I will trust the lower number, but if anyone has a better source that would be great.
**Based off of the announced 35 pounds / month cost => 60$ / month)
lycopene with milk & soya bean proteins
Submitted on July 2nd, 2009 by Anonymousplz tell me detail information regarding this combinations