New Molecule Discovered That May Suppress Hunger

As the holidays quickly approach, many weight-loss resolutions are made in order to start the new year fresh. However, new discoveries may help with the battle of the bulge.

Researchers at Yale University have discovered a new molecule that could suppress hunger after eating a fatty meal.

This research suggests that the molecule may help control how much people and animals eat. A family of lipids called N-acylphosphatidylethanolamines (NAPEs) were studied. These lipids are synthesized and secreted into the blood by the small intestine after eating fatty foods.

Conducting their study on mice and rats, the researchers found that those injected regularly with NAPEs ate less food and lost weight. Being treated with NAPEs seemed to reduce the activity of the neurons in the brain controlling hunger.

Researchers are now planning on carrying out their research on humans but will first study non-human primates. “If chronic NAPE treatment is well tolerated and can cause weight loss by a reduction of food intake, we would have strong impetus to move forward with human NAPE trials,” stated Gerald I. Shulman, Yale professor of medicine and cellular & molecular physiology and a Howard Hughes Medical Institute investigator.

This research is published in the November 26 issue of the journal Cell.


Source: Yale Univ. News Release

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Nov 27, 2008
by Anonymous

Pills Do the Trick

The fat-burning pill ( and the exercise pill ( have both been scientifically validated, so who cares how much we eat? If the FDA would just speed up its approval process, we'll be home-free!

Nov 28, 2008
by Anonymous


Whey protein comes from milk, is fairly cheap, and has been documented to reduce hunger/burn fat/build muscle/bolster the immune system/have possible anti-carcinogenic effects.

Makes you wonder why the government is looking for answers on the moon when the solution is in the fridge (figuratively speaking).