New Solution For Tooth Decay: Just Grow A New Tooth


Cavity seen on an x-ray.: image via webMD.comCavity seen on an x-ray.: image via

The main treatment for cavities - drill and fill - has given the dental profession a bad rep.  Ask people what they hate to do most, and I bet half of them will say "Going to the dentist."  But now, French researchers at the National Institute for Health and Medical Research in Paris have developed a painless and simple method that could very soon put an end to fillings.  You know - Novocaine, water, air, drilling, sore mouth, and chemical taste?

Fillings are used to fill holes left by tooth decay. (Do yourself a favor and don't check out Google images for 'tooth decay.')  Decay is caused by bacteria called streptococcus mutans, and yes it does feed on sugar in the diet. The French team, rather than identify other fillers for the holes, tried to find a way to make the tooth grow back to fill in the hole.

They made a gel substance from MSH (melanocyte-stimulating hormone) with poly-L-glutamic acid, a strong survivor often used to transport drugs through our bodies because it can fight off stomach acids that might destroy the medication. The researchers rubbed the gel on dental pulp fibroblasts taken from human tooth tissue and found that the gel triggered growth of new cells and adhered to each other.

MSH is a substance that is naturally produced by the pituitary gland and it is active in determining the lightness or darkness of our skin color.  But recently, MSH has been identified as playing a crucial role in bone regeneration, which is what gave the researchers the idea to try it for tooth regeneration.

The researchers experimented with the gel on mice with dental cavities and the cavities disappeared within one month.  It took the same amount of time to restore the human samples to form healthy new tooth tissue.  Though it won't be available to dentists for 3 to 5 years, there's one thing you can count on: there won't be a hole in your tooth any more. That tissue you identify as "tooth" will come back and look just like your original - a brand new tooth.

Isn't science great?


The complete study is published by the American Chemical Society in its journal ACS Nano. Source: Daily Mail.

Jul 29, 2010
by Anonymous


WAY TOO LATE FOR ME..............

Jul 30, 2010
by Anonymous

May they be quick in finishing it!

Cosmetic dental surgery break throughs like this are tremendously exciting. The frustrating part is that there is a very long way to go between experimental break-through and FDA-approved human procedure.
With luck they'll be working very hard and people like us can start offering this service as soon as possible!
In the meantime, there are plenty of pain-releaving techniques that any good cosmetic dental surgeon can offer. These include anaesthetic gels, creams, injections and even sedation.
So it really doesn't have to be as bad as the article implies! (Honest!)

Sep 6, 2010
by Anonymous


If it gets FDA approval and shows to have a high success rate it will be a win-win for everybody. More jobs created and more patients willing to visit the dentist along with the obvious advancement it presents in the field of dentistry. Will not probably replace fillings; rather provide another option for patients. I know I would rather have a biological filling and would be willing to pay more for one..

Sep 10, 2010
by Anonymous


i have a friend call an the friend hab=ve a teeth afaction and the teeth has hole ehat is the solution

Sep 18, 2010
by Anonymous


crazy and george need english lessons

Dec 12, 2010
by Anonymous

Need to Grow Tooth.

I would like to contact NHS in Paris - please.jt

May 21, 2011
by Anonymous


A tooth decay is formed upon dissolution of minerals of the enamel (the most outer part of the tooth) and subsequently dentin (the inner layer). Enamel however, has no capability of SELF-regeneration. some early caries would stop and potentially reversed upon good oral hygiene and in the presence of high salivary flow, ions and other factors but enamel can't restore itself like dentin can. The Odontoblasts, which are a more specialized form of fibroblasts in the pulp already do make new dentin in response to caries. I don't understand how stimulating them can have any effects on the enamel though.

Jun 25, 2011
by Anonymous

I think its amazing!!!!

I think its amazing!!!!

Jan 3, 2012
by Anonymous