Human molar scaffolding created by Dr. Jeremy Mao: ©Columbia University School Of Medicine
Dracula may soon get a run for his... fast-growing canines!
A pioneering technology in dental medicine that has the
potential to make dentures and dental implants obsolete was announced by Columbia University Medical Center. The new technology, created by Dr. Jeremy Mao of the Tissue Engineering and Regenerative Medicine Laboratory at the Medical Center, homes stem cells to a 3-dimensional scaffold in the space left by the former tooth.
Dr. Mao has successful grown teeth in animal models by homing their body's stem cells to a micro-channeled scaffold in the tooth socket. The scaffold, which is made of all natural material and integrated into surrounding tissue keeps the shape of the tooth until periodontal ligaments and new alveolar bone has grown and, finally, until the tooth itself grows orthotopically.
“A key consideration in tooth regeneration is finding a cost-effective
approach that can translate into therapies for patients who cannot
afford or who aren’t good candidates for dental implants,” Dr. Mao
says. “Cell-homing-based tooth regeneration may provide a tangible
pathway toward clinical translation.”
If you, or someone you know has dentures or has experienced tooth
implantation, you know that a new technology that enables a tooth to
grow back 'naturally' right in the space of the lost tooth, without
misfitting, without repeated, extensive office visits, and without spending a year or more in the
healing process... will be a welcomed miracle!
Columbia University School of Medicine via PopSci